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Génomique du cancer : du banc à la médecine personnalisée 9780123969675

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No highlighting/underlining. Moderate wear. Small tear in cover reinforced with clear tape.
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Lieu : Waltham, Massachusetts, États-Unis
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Numéro de l'objet eBay :115874518528
Dernière mise à jour : nov. 27, 2023 13:43:15 HNEAfficher toutes les modificationsAfficher toutes les modifications

Caractéristiques de l'objet

État
Acceptable
Un livre présentant des traces d'usure apparentes. Sa couverture peut être endommagée, mais elle est globalement intacte. Sa reliure peut être légèrement endommagée, mais elle est globalement intacte. Il est possible que les marges portent des inscriptions ou que des passages aient été soulignés ou surlignés, mais il n'y a aucune page manquante et rien ne compromet la lisibilité ou la compréhension du texte. Afficher toutes les définitions d'état(s'ouvre dans une nouvelle fenêtre ou un nouvel onglet)
Remarques du vendeur
“No highlighting/underlining. Moderate wear. Small tear in cover reinforced with clear tape.”
ISBN
9780123969675
Publication Year
2014
Type
Textbook
Format
Hardcover
Language
English
Subject Area
Science, Medical
Publication Name
Cancer Genomics : from Bench to Personalized Medicine
Author
Jason N. Berman
Item Length
10.9 in
Publisher
Elsevier Science & Technology
Item Width
8.5 in
Subject
Life Sciences / Genetics & Genomics, Oncology
Number of Pages
510 Pages

À propos de ce produit

Product Information

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment. Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics. Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.

Product Identifiers

Publisher
Elsevier Science & Technology
ISBN-10
0123969670
ISBN-13
9780123969675
eBay Product ID (ePID)
167830288

Product Key Features

Author
Jason N. Berman
Publication Name
Cancer Genomics : from Bench to Personalized Medicine
Format
Hardcover
Language
English
Subject
Life Sciences / Genetics & Genomics, Oncology
Publication Year
2014
Type
Textbook
Subject Area
Science, Medical
Number of Pages
510 Pages

Dimensions

Item Length
10.9 in
Item Width
8.5 in

Additional Product Features

Intended Audience
Scholarly & Professional
Lc Classification Number
Rc268.4
Reviews
"...provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies."-- Anticancer Research 34, 2014, ".provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies."-- Anticancer Research 34, 2014
Table of Content
Introduction1. Historical Overview Methodological Approaches and Background2. Expression Arrays (SNPs, etc.)3. Tissue micro-arrays (breast, ovarian) 4. Next generation sequencing (DNAseq) 5. RNAseq (breast cancer, sarcomas)6. Epigenetic Analyses7. Pharmcogenomics8. Biomarker discovery through genomics 9. Preclinical models for genomics (cell culture, transgenic animals, xenografts) 10. Bioinformatics and computational methods for data analysis11. Genomic Resource Projects - The Cancer Genome Atlas (TCGA) International Cancer Genome Consortium (ICGC) Ethics of Genomics Research 12. Ethics of Genomics Research The Genomics, Epigenomics and Transcriptomics of Cancer13. Somatic mutations, Transcription and Epigenetics Overview Adult Solid Tumors14. Lung Cancer15. Breast Cancer16. Prostate Cancer17. Colon Cancer18. Thyroid Cancer Age Non-specific Tumors and Hematopoietic Malignancies19. ALL 20. AML21. NHL22. Multiple Myeloma23. Brain Tumors Pediatric Cancers24. Neuroblastoma25. Soft tissue sarcomas26. Osteosarcoma27. Wilms Tumors Germline Mutations and Hereditary Cancer Syndromes 28. Germline Mutations and Hereditary Cancer Syndromes Future Directions29. The role of microRNAs and ultraconserved non-coding RNAs in cancer30. Environmental impact on cancer genomics
Copyright Date
2014
Dewey Decimal
616.994042
Dewey Edition
23

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